If you are like me, when you are getting ready to book a flight online, you just don't pick your favorite airline and book the tickets - you comparison shop. Well this process is not only incredibly tedious, but completely ineffective. I say this now because I have finally found a great web site and resource for searching for the lowest airfare - domestic or international.
Mobissimo.com scours 173 sites directly for the dates and specifications you are looking for in a flight. They look at all the major airlines, travel agent sites, you name it. If you only want a non-stop flight, you can specify that, you can look for just a one-way fare or trips with multiple stops. This site really is ingenious and works. What's funny now is that airlines now usually offer their lowest rates directly on their web site, taking out middle men like Orbitz.com and Travelocity.com.
Besides an airfare search, you can also do the same for hotels and rental cars. I suggest you add this one to your bookmarks because it will win you over the first time it helps you save $100+ on tickets :)